Page 53 - 2017Spring
P. 53

provements in computer-processing power and data-trans- fer bandwidth are allowing the emergence of high-speed imaging methods based on unfocused plane and diverging waves. Overall, these are exciting times for medical ultra- sound imaging that continues to offer surprises, considering that the basic methods of ultrasound imaging were perfect- ed many decades ago.
Acknowledgments
Portions of this work were supported by Grant EY025215 from the National Eye Institute, National Institutes of Health, to Ronald H. Silverman and Grant EY024434 from the National Eye Institute and Grant EB022950 from the Na- tional Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, to Jeffrey A. Ketterling. We thank Raksha Urs and Orlando Aristizábal for helpful input and discussions.
Biosketches
Jeffrey A. Ketterling is the associate research director of the Frederic Lizzi Center for Biomedical Engineering at the Riverside Research Institute in New York, NY. His past work has focused on high-frequency ultrasound and, in par- ticular, high-frequency annular arrays
for small-animal and ophthalmic imaging applications. He was the technical chair of the Biomedical Acoustics Com- mittee of the Acoustical Society of America (ASA) from 2008 to 2011 and is a Fellow of the ASA. He received his PhD degree in mechanical engineering from Yale University, New Haven, CT, in 1999.
Ronald Silverman is a professor of oph- thalmic science at Columbia University Medical Center (CUMC) in New York, NY. His postgraduate training was in bioengineering and computer science at Polytechnic University in Brooklyn, NY. After 28 years of research and the clini-
cal application of ultrasound in the Department of Ophthal- mology at Weill-Cornell Medical Center in New York, NY, he moved to the Harkness Eye Institute of CUMC, where he continues his research in ultrasound for imaging the eye. His primary interests now include high-frequency ultrasound for biometric and biomechanical mapping of the cornea and ultrafast imaging of ocular blood flow.
References
Aristizábal, O., Mamou, J., Ketterling, J. A., and Turnbull, D. H. (2013). High-throughput, high-frequency 3-D ultrasound for in utero analysis of embryonic mouse brain development. Ultrasound in Medicine and Biology 39, 2321-2332.
Cannata, J. M., Ritter, T. A., Chen, W. H., Silverman, R. H., and Shung, K. K. (2003). Design of efficient, broadband single-element (20-80 MHz) ultra- sonic transducers for medical imaging applications. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 50, 1548-1557.
Chérin, E., Williams, R., Needles, A., Liu, G., White, C., Brown, A. S., Zhou, Y. Q., and Foster, F. S. (2006). Ultrahigh frame rate retrospective ultra- sound microimaging and blood flow visualization in mice in vivo. Ultra- sound in Medicine and Biology 32, 683-691.
Emelianov, S. Y., Li, P.-C., and O’Donnell, M. (2009). Photoacoustics for molecular imaging and therapy. Physics Today 62, 34-39.
Foster, F. S., Mehi, J., Lukacs, M., Hirson, D., White, C., Chaggares, C., and Needles, A. (2009). A new 15-50 MHz array-based micro-ultrasound scanner for preclinical imaging. Ultrasound in Medicine and Biology 35, 1700-1708.
Foster, F. S., Hossack, J., and Adamson, S. L. (2011). Micro-ultrasound for preclinical imaging. Interface Focus 1, 576-601.
Hu, C. H., Xu, X. C., Cannata, J. M., Yen, J. T., and Shung, K. K. (2006). De- velopment of a real-time, high-frequency ultrasound digital beamformer for high-frequency linear array transducers. IEEE Transactions on Ultra- sonics, Ferroelectrics, and Frequency Control 53, 317-323.
Ketterling, J. A., Aristizábal, O., Turnbull, D. H., and Lizzi, F. L. (2005). De- sign and fabrication of a 40-MHz annular array transducer. IEEE Transac- tions on Ultrasonics, Ferroelectrics, and Frequency Control 52, 672-681.
Ma, T., Zhou, B., Hsiai, T. K., and Shung, K. K. (2016). A review of intra- vascular ultrasound-based multimodal intravascular imaging: The syner- gistic approach to characterizing vulnerable plaques. Ultrasonic Imaging 38, 314-331.
O'Donnell, M., Eberle, M. J., Stephens, D. N., Litzza, J. L., San Vicente, K,, and Shapo, B. M. (1997). Synthetic phased arrays for intraluminal imaging of coronary arteries. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 53, 317-323.
Pavlin, C. J., Sherar, M., and Foster, F. S. (1990). Subsurface ultrasound bio- microscopic imaging of the intact eye. Ophthalmology 97, 244-250.
Pavlin, C. J., Harasiewicz, K., Sherar, M. D., and Foster, F. S. (1991) Clinical use of ultrasound biomicroscopy. Ophthalmology 98, 287-295.
Sherar, M. D., and Foster, F. S. (1989). The design and fabrication of high- frequency poly(vinylidene fluoride) transducers. Ultrasonic Imaging 11, 75-94.
Silverman, R. H., Ketterling, J. A., Mamou, J., Lloyd, H. O., Filoux, E., and Coleman, D. J. (2011). Pulse-encoded ultrasound imaging of the vitreous with an annular array. Ophthalmic Surgery Lasers Imaging Retina 43, 82-86.
Tanter, M., and Fink, M. (2014). Ultrafast imaging in biomedical ultra- sound. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 61, 102-119.
Urs, R., Silverman, R. H., and Ketterling, J. A. (2016). Ultrafast ultrasound imaging of ocular anatomy and blood flow. Investigative Ophthalmology & Visual Science 57, 3810-3816.
Zhou, Q., Lau, S., Wu, D., and Shung, K. K. (2011). Piezoelectric films for high frequency ultrasonic transducers in biomedical applications. Progress in Materials Science 56, 139-174.
Zhou, Y. Q., Foster, F. S., Qu, D. W., Zhang, M., Harasiewicz, K. A., and Adamson, S. L. (2002). Applications for multifrequency ultrasound biomi- croscopy in mice from implantation to adulthood. Physiological Genomics 10, 113-126.
      Spring 2017 | Acoustics Today | 51







































































   51   52   53   54   55